Analysing the protection from respiratory tract infections and allergic diseases early in life by human milk components: the PRIMA birth cohort - BMC Infectious Diseases - BMC Infectious Diseases

  • Kutsaya A, Teros-Jaakkola T, Kakkola L, Toivonen L, Peltola V, Waris M, et al. Prospective clinical and serological follow-up in early childhood reveals a high rate of subclinical RSV infection and a relatively high reinfection rate within the first 3 years of life. Epidemiol Infect. 2016;144(8):1622–33.

    CAS  PubMed  Google Scholar 

  • Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, et al. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1459–544.

    Google Scholar 

  • Pneumonia Etiology Research for Child Health Study G. Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study. Lancet. 2019;394(10200):757–79.

    Google Scholar 

  • Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet. 2010;375(9725):1545–55.

    PubMed  PubMed Central  Google Scholar 

  • Reeves RM, van Wijhe M, Tong S, Lehtonen T, Stona L, Teirlinck AC, et al. Respiratory syncytial virus-associated hospital admissions in children younger than 5 years in 7 European countries using routinely collected datasets. J Infect Dis. 2020;222(Supplement_7):S599–605.

    PubMed  Google Scholar 

  • Yu ZT, Chen C, Newburg DS. Utilization of major fucosylated and sialylated human milk oligosaccharides by isolated human gut microbes. Glycobiology. 2013;23(11):1281–92.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Isaacs D. Should respiratory care in preterm infants include prophylaxis against respiratory syncytial virus? The case against. Paediatr Respir Rev. 2013;14(2):128–9.

    PubMed  Google Scholar 

  • Meijboom MJ, Rozenbaum MH, Benedictus A, Luytjes W, Kneyber MC, Wilschut JC, et al. Cost-effectiveness of potential infant vaccination against respiratory syncytial virus infection in The Netherlands. Vaccine. 2012;30(31):4691–700.

    CAS  PubMed  Google Scholar 

  • Bos JM, Rietveld E, Moll HA, Steyerberg EW, Luytjes W, Wilschut JC, et al. The use of health economics to guide drug development decisions: determining optimal values for an RSV-vaccine in a model-based scenario-analytic approach. Vaccine. 2007;25(39–40):6922–9.

    CAS  PubMed  Google Scholar 

  • Jansen AG, Sanders EA, Hoes AW, van Loon AM, Hak E. Influenza- and respiratory syncytial virus-associated mortality and hospitalisations. Eur Respir J. 2007;30(6):1158–66.

    CAS  PubMed  Google Scholar 

  • Fauroux B, Simões EAF, Checchia PA, Paes B, Figueras-Aloy J, Manzoni P, et al. The burden and long-term respiratory morbidity associated with respiratory syncytial virus infection in early childhood. Infect Dis Therapy. 2017;6(2):173–97.

    Google Scholar 

  • Lawrence RM, Lawrence RA. Breastfeeding: more than just good nutrition. Pediatr Rev. 2011;32(7):267–80.

    PubMed  Google Scholar 

  • Munblit D, Peroni DG, Boix-Amorós A, Hsu PS, Van't Land B, Gay MCL, et al. Human milk and allergic diseases: an unsolved puzzle. Nutrients. 2017. https://doi.org/10.3390/nu9080894.

    Article  PubMed  PubMed Central  Google Scholar 

  • Ajetunmobi OM, Whyte B, Chalmers J, Tappin DM, Wolfson L, Fleming M, et al. Breastfeeding is associated with reduced childhood hospitalization: evidence from a Scottish Birth Cohort (1997–2009). J Pediatr. 2015;166(3):620-625 e4.

    PubMed  PubMed Central  Google Scholar 

  • Walker WA, Iyengar RS. Breast milk, microbiota, and intestinal immune homeostasis. Pediatr Res. 2015;77(1–2):220–8.

    CAS  PubMed  Google Scholar 

  • Duijts L, Jaddoe VW, Hofman A, Moll HA. Prolonged and exclusive breastfeeding reduces the risk of infectious diseases in infancy. Pediatrics. 2010;126(1):e18-25.

    PubMed  Google Scholar 

  • Shi T, Balsells E, Wastnedge E, Singleton R, Rasmussen ZA, Zar HJ, et al. Risk factors for respiratory syncytial virus associated with acute lower respiratory infection in children under five years: systematic review and meta-analysis. J Glob Health. 2015;5(2): 020416.

    PubMed  PubMed Central  Google Scholar 

  • Rietveld E, De Jonge HC, Polder JJ, Vergouwe Y, Veeze HJ, Moll HA, et al. Anticipated costs of hospitalization for respiratory syncytial virus infection in young children at risk. Pediatr Infect Dis J. 2004;23(6):523–9.

    PubMed  Google Scholar 

  • Levine OS, Farley M, Harrison LH, Lefkowitz L, McGeer A, Schwartz B. Risk factors for invasive pneumococcal disease in children: a population-based case-control study in North America. Pediatrics. 1999;103(3):E28.

    CAS  PubMed  Google Scholar 

  • Dharan NJ, Sokolow LZ, Cheng PY, Gargiullo P, Gershman K, Lynfield R, et al. Child, household, and caregiver characteristics associated with hospitalization for influenza among children 6–59 months of age: an emerging infections program study. Pediatr Infect Dis J. 2014;33(6):e141–50.

    PubMed  PubMed Central  Google Scholar 

  • Lamberti LM, Fischer Walker CL, Noiman A, Victora C, Black RE. Breastfeeding and the risk for diarrhea morbidity and mortality. BMC Public Health. 2011;11(Suppl 3):S15.

    PubMed  PubMed Central  Google Scholar 

  • Lodge CJ, Tan DJ, Lau MX, Dai X, Tham R, Lowe AJ, et al. Breastfeeding and asthma and allergies: a systematic review and meta-analysis. Acta Paediatr. 2015;104(467):38–53.

    CAS  PubMed  Google Scholar 

  • Klopp A, Vehling L, Becker AB, Subbarao P, Mandhane PJ, Turvey SE, et al. Modes of infant feeding and the risk of childhood asthma: a prospective birth cohort study. J Pediatr. 2017;190:192–292.

    PubMed  Google Scholar 

  • Azad MB, Vehling L, Lu Z, Dai D, Subbarao P, Becker AB, et al. Breastfeeding, maternal asthma and wheezing in the first year of life: a longitudinal birth cohort study. Eur Respir J. 2017. https://doi.org/10.1183/13993003.02019-2016.

    Article  PubMed  Google Scholar 

  • Flohr C, Nagel G, Weinmayr G, Kleiner A, Strachan DP, Williams HC, et al. Lack of evidence for a protective effect of prolonged breastfeeding on childhood eczema: lessons from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Two. Br J Dermatol. 2011;165(6):1280–9.

    CAS  PubMed  Google Scholar 

  • Pesonen M, Kallio MJ, Ranki A, Siimes MA. Prolonged exclusive breastfeeding is associated with increased atopic dermatitis: a prospective follow-up study of unselected healthy newborns from birth to age 20 years. Clin Exp Allergy. 2006;36(8):1011–8.

    CAS  PubMed  Google Scholar 

  • Giwercman C, Halkjaer LB, Jensen SM, Bonnelykke K, Lauritzen L, Bisgaard H. Increased risk of eczema but reduced risk of early wheezy disorder from exclusive breast-feeding in high-risk infants. J Allergy Clin Immunol. 2010;125(4):866–71.

    PubMed  Google Scholar 

  • Han SM, Binia A, Godfrey KM, El-Heis S, Cutfield WS. Do human milk oligosaccharides protect against infant atopic disorders and food allergy? Nutrients. 2020. https://doi.org/10.3390/nu12103212.

    Article  PubMed  PubMed Central  Google Scholar 

  • Lodge CJ, Lowe AJ, Milanzi E, Bowatte G, Abramson MJ, Tsimiklis H, et al. Human milk oligosaccharide profiles and allergic disease up to 18 years. J Allergy Clin Immunol. 2020. https://doi.org/10.1016/j.jaci.2020.06.027.

    Article  PubMed  Google Scholar 

  • Mazur NI, Martinón-Torres F, Baraldi E, Fauroux B, Greenough A, Heikkinen T, et al. Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics. Lancet Respir Med. 2015;3(11):888–900.

    PubMed  Google Scholar 

  • Breakey AA, Hinde K, Valeggia CR, Sinofsky A, Ellison PT. Illness in breastfeeding infants relates to concentration of lactoferrin and secretory Immunoglobulin A in mother's milk. Evol Med Public Health. 2015;2015(1):21–31.

    PubMed  PubMed Central  Google Scholar 

  • Ramani S, Stewart CJ, Laucirica DR, Ajami NJ, Robertson B, Autran CA, et al. Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection. Nat Commun. 2018;9(1):5010.

    PubMed  PubMed Central  Google Scholar 

  • Barton SJ, Murray R, Lillycrop KA, Inskip HM, Harvey NC, Cooper C, et al. FUT2 genetic variants and reported respiratory and gastrointestinal illnesses during infancy. J Infect Dis. 2019;219(5):836–43.

    CAS  PubMed  Google Scholar 

  • Arslanoglu S, Moro GE, Boehm G. Early supplementation of prebiotic oligosaccharides protects formula-fed infants against infections during the first 6 months of life. J Nutr. 2007;137(11):2420–4.

    CAS  PubMed  Google Scholar 

  • Moro G, Arslanoglu S, Stahl B, Jelinek J, Wahn U, Boehm G. A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age. Arch Dis Child. 2006;91(10):814–9.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Gruber C, van Stuijvenberg M, Mosca F, Moro G, Chirico G, Braegger CP, et al. Reduced occurrence of early atopic dermatitis because of immunoactive prebiotics among low-atopy-risk infants. J Allergy Clin Immunol. 2010;126(4):791–7.

    PubMed  Google Scholar 

  • Ranucci G, Buccigrossi V, Borgia E, Piacentini D, Visentin F, Cantarutti L, et al. Galacto-oligosaccharide/polidextrose enriched formula protects against respiratory infections in infants at high risk of atopy: a randomized clinical trial. Nutrients. 2018. https://doi.org/10.3390/nu10030286.

    Article  PubMed  PubMed Central  Google Scholar 

  • Arslanoglu S, Moro GE, Boehm G, Wienz F, Stahl B, Bertino E. Early neutral prebiotic oligosaccharide supplementation reduces the incidence of some allergic manifestations in the first 5 years of life. J Biol Regul Homeost Agents. 2012;26(3 Suppl):49–59.

    CAS  PubMed  Google Scholar 

  • Ayechu-Muruzabal V, van Stigt AH, Mank M, Willemsen LEM, Stahl B, Garssen J, et al. Diversity of human milk oligosaccharides and effects on early life immune development. Front Pediatr. 2018;6:239.

    PubMed  PubMed Central  Google Scholar 

  • Laucirica DR, Triantis V, Schoemaker R, Estes MK, Ramani S. Milk oligosaccharides inhibit human rotavirus infectivity in MA104 cells. J Nutr. 2017;147(9):1709–14.

    CAS  PubMed  PubMed Central  Google Scholar 

  • van Erp EA, Lakerveld AJ, de Graaf E, Larsen MD, Schepp RM, Hipgrave Ederveen AL, et al. Natural killer cell activation by respiratory syncytial virus-specific antibodies is decreased in infants with severe respiratory infections and correlates with Fc-glycosylation. Clin Transl Immunol. 2020;9(2): e1112.

    Google Scholar 

  • Zehra S, Khambati I, Vierhout M, Mian MF, Buck R, Forsythe P. Human milk oligosaccharides attenuate antigen-antibody complex induced chemokine release from human intestinal epithelial cell lines. J Food Sci. 2018;83(2):499–508.

    CAS  PubMed  Google Scholar 

  • Xiao L, van De Worp WR, Stassen R, van Maastrigt C, Kettelarij N, Stahl B, et al. Human milk oligosaccharides promote immune tolerance via direct interactions with human dendritic cells. Eur J Immunol. 2019;49(7):1001–14.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Xiao L, Van't Land B, Engen PA, Naqib A, Green SJ, Nato A, et al. Human milk oligosaccharides protect against the development of autoimmune diabetes in NOD-mice. Sci Rep. 2018;8(1):3829.

    PubMed  PubMed Central  Google Scholar 

  • Backhed F, Roswall J, Peng Y, Feng Q, Jia H, Kovatcheva-Datchary P, et al. Dynamics and stabilization of the human gut microbiome during the first year of life. Cell Host Microbe. 2015;17(5):690–703.

    PubMed  Google Scholar 

  • Rautava S. Early microbial contact, the breast milk microbiome and child health. J Dev Orig Health Dis. 2016;7(1):5–14.

    CAS  PubMed  Google Scholar 

  • Hassiotou F, Hepworth AR, Metzger P, Tat Lai C, Trengove N, Hartmann PE, et al. Maternal and infant infections stimulate a rapid leukocyte response in breastmilk. Clin Transl Immunol. 2013;2(4): e3.

    CAS  Google Scholar 

  • Timby N, Domellöf M, Lönnerdal B, Hernell O. Supplementation of infant formula with bovine milk fat globule membranes. Adv Nutr. 2017;8(2):351–5.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Verhasselt V, Milcent V, Cazareth J, Kanda A, Fleury S, Dombrowicz D, et al. Breast milk-mediated transfer of an antigen induces tolerance and protection from allergic asthma. Nat Med. 2008;14(2):170–5.

    CAS  PubMed  Google Scholar 

  • Dawod B, Marshall JS. Cytokines and soluble receptors in breast milk as enhancers of oral tolerance development. Front Immunol. 2019;10:16.

    CAS  PubMed  PubMed Central  Google Scholar 

  • van den Elsen LWJ, Garssen J, Burcelin R, Verhasselt V. Shaping the gut microbiota by breastfeeding: the gateway to allergy prevention? Front Pediatr. 2019;7:47.

    PubMed  PubMed Central  Google Scholar 

  • Kosaka N, Izumi H, Sekine K, Ochiya T. microRNA as a new immune-regulatory agent in breast milk. Silence. 2010;1(1):7.

    PubMed  PubMed Central  Google Scholar 

  • Twigger AJ, Kuffer GK, Geddes DT, Filgueria L. Expression of granulisyn, perforin and granzymes in human milk over lactation and in the case of maternal infection. Nutrients. 2018. https://doi.org/10.3390/nu10091230.

    Article  PubMed  PubMed Central  Google Scholar 

  • Koletzko B. Human milk lipids. Ann Nutr Metab. 2016;69(Suppl 2):28–40.

    PubMed  Google Scholar 

  • Ballard O, Morrow AL. Human milk composition: nutrients and bioactive factors. Pediatr Clin North Am. 2013;60(1):49–74.

    PubMed  PubMed Central  Google Scholar 

  • Kummeling I, Mills EN, Clausen M, Dubakiene R, Pérez CF, Fernández-Rivas M, et al. The EuroPrevall surveys on the prevalence of food allergies in children and adults: background and study methodology. Allergy. 2009;64(10):1493–7.

    CAS  PubMed  Google Scholar 

  • Zonneveld MI, Brisson AR, van Herwijnen MJ, Tan S, van de Lest CH, Redegeld FA, et al. Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures. J Extracell Vesicles. 2014. https://doi.org/10.3402/jev.v3.24215.

    Article  PubMed  PubMed Central  Google Scholar 

  • Mank M, Welsch P, Heck AJR, Stahl B. Label-free targeted LC-ESI-MS(2) analysis of human milk oligosaccharides (HMOS) and related human milk groups with enhanced structural selectivity. Anal Bioanal Chem. 2019;411(1):231–50.

    CAS  PubMed  Google Scholar 

  • van Gageldonk PG, van Schaijk FG, van der Klis FR, Berbers GA. Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus. J Immunol Methods. 2008;335(1–2):79–89.

    PubMed  Google Scholar 

  • de Voer RM, van der Klis FR, Engels CW, Rijkers GT, Sanders EA, Berbers GA. Development of a fluorescent-bead-based multiplex immunoassay to determine immunoglobulin G subclass responses to Neisseria meningitidis serogroup A and C polysaccharides. Clin Vaccine Immunol. 2008;15(8):1188–93.

    PubMed  PubMed Central  Google Scholar 

  • Smits GP, van Gageldonk PG, Schouls LM, van der Klis FR, Berbers GA. Development of a bead-based multiplex immunoassay for simultaneous quantitative detection of IgG serum antibodies against measles, mumps, rubella, and varicella-zoster virus. Clin Vaccine Immunol. 2012;19(3):396–400.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Tcherniaeva I, den Hartog G, Berbers G, van der Klis F. The development of a bead-based multiplex immunoassay for the detection of IgG antibodies to CMV and EBV. J Immunol Methods. 2018;462:1–8.

    CAS  PubMed  Google Scholar 

  • den Hartog G, van Binnendijk R, Buisman AM, Berbers GAM, van der Klis FRM. Immune surveillance for vaccine-preventable diseases. Expert Rev Vaccines. 2020;19(4):327–39.

    Google Scholar 

  • den Hartog G, Schepp RM, Kuijer M, GeurtsvanKessel C, van Beek J, Rots N, et al. SARS-CoV-2-specific antibody detection for seroepidemiology: a multiplex analysis approach accounting for accurate seroprevalence. J Infect Dis. 2020;222(9):1452–61.

    Google Scholar 

  • Donovan SM, Comstock SS. Human milk oligosaccharides influence neonatal mucosal and systemic immunity. Ann Nutr Metab. 2016;69(Suppl 2):42–51.

    PubMed  Google Scholar 

  • Lopez-Rincon A, Mendoza-Maldonado L, Martinez-Archundia M, Schonhuth A, Kraneveld AD, Garssen J, et al. Machine learning-based ensemble recursive feature selection of circulating miRNAs for cancer tumor classification. Cancers (Basel). 2020. https://doi.org/10.3390/cancers12071785.

    Article  PubMed  PubMed Central  Google Scholar 

  • Lopez-Rincon A, Martinez-Archundia M, Martinez-Ruiz GU, Schoenhuth A, Tonda A. Automatic discovery of 100-miRNA signature for cancer classification using ensemble feature selection. BMC Bioinformatics. 2019;20(1):480.

    PubMed  PubMed Central  Google Scholar 

  • Metselaar PI, Mendoza-Maldonado L, Li Yim AYF, Abarkan I, Henneman P, Te Velde AA, et al. Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome. Sci Rep. 2021;11(1):4541.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Simundic AM. Measures of diagnostic accuracy: basic definitions. EJIFCC. 2009;19(4):203–11.

    PubMed  PubMed Central  Google Scholar 

  • Mandrekar JN. Receiver operating characteristic curve in diagnostic test assessment. J Thorac Oncol. 2010;5(9):1315–6.

    PubMed  Google Scholar 

  • Williams BG, Gouws E, Boschi-Pinto C, Bryce J, Dye C. Estimates of world-wide distribution of child deaths from acute respiratory infections. Lancet Infect Dis. 2002;2(1):25–32.

    PubMed  Google Scholar 

  • Shi T, McAllister DA, O'Brien KL, Simoes EAF, Madhi SA, Gessner BD, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. Lancet. 2017;390(10098):946–58.

    PubMed  PubMed Central  Google Scholar 

  • Blanken MO, Rovers MM, Molenaar JM, Winkler-Seinstra PL, Meijer A, Kimpen JL, et al. Respiratory syncytial virus and recurrent wheeze in healthy preterm infants. N Engl J Med. 2013;368(19):1791–9.

    CAS  PubMed  Google Scholar 

  • Mejias A, Wu B, Tandon N, Chow W, Varma R, Franco E, et al. Risk of childhood wheeze and asthma after respiratory syncytial virus infection in full-term infants. Pediatr Allergy Immunol. 2020;31(1):47–56.

    PubMed  Google Scholar 

  • Marchant A, Sadarangani M, Garand M, Dauby N, Verhasselt V, Pereira L, et al. Maternal immunisation: collaborating with mother nature. Lancet Infect Dis. 2017;17(7):e197–208.

    PubMed  Google Scholar 

  • Comments

    Popular posts from this blog